Not surprisingly, the population of the Home was greater during the Depression than during any other time in its history. Despite the economic ills gripping the country, the children at the Home were well looked after. A story from the February 17, 1935 edition of the Toledo Times notes that in the previous nine years, only one child had died while residing at the Home, "and that of an incurable disease contracted elsewhere." The Times cited a survey listing children in the Lucas County home as having the best teeth among children in similar institutions across the country. The story also referred to the daily regimen of 27 square feet of coffee cake and 200 loaves of bread made in the kitchen.
Among the approximately 70 employees were a physician, six nurses who ran the Home's hospital, and a visiting dentist. At this time, children of grade-school age were educated at the Home. Those of junior-high age attended school at Ft. Miami, and high school students went to Maumee High.